IEEE System, Man, and Cybernetics Society announces the 19th International Conference on System of Systems Engineering (SoSE) with its vast ramifications in numerous engineering fields such as control, computing, communication, information technology, artificial intelligence, and in applications such manufacturing, defense, national security, aerospace, aeronautics, energy, environment, healthcare, and transportation. The conference theme is “AI Role in System of Systems Engineering”. Papers on theories, methodologies, and applications of System of Systems Engineering in science, technology, industry, and education are welcome.